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Exhibits wide range of altitudinal and habitat requirements. In vitro time-kill kinetics antibacterial study of Acacia nilotica was assessed against Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus determined by plate count technique and analyzed by percentage and log reduction. It is a complex species with nine subspecies, of which six are native to the African tropics and three others are native to the Indian subcontinent. Materials and Methods Tripti, B.G. Search engines such as Google, Bing and Baidu a, journals such as PubMed, Scopus, CAS, CABI, HIN, to be the most cited to cause observable clinical signs of toxicity and o, the history of human life. Methods: Scientific information about the toxicity and or safety of A. nilotica reported elsewhere were reviewed. Plants. It is very important to dispose sufficient knowledge on what are reported concerning its toxicity profile. Get Involved in EISAA. Oxford Univ, Sotohy SA, Sayed AN, Ahmed MM. Top of page A. nilotica is a pioneer species that is relatively fast growing on arid sites. Acacia nilotica. albicans , associated with fluconazole resistance with bioactive compounds from Acacia nilotica In present 2. 2017;22(5). kingdom. Antiplatelet Aggregatory Activity: A study was carried out by Bukhtiar H. Shah et al that the extract of Acacia nilotica (A. nilotica)have capacity to blocked platelet aggregation mediated by platelet agonists, arachidonic acid (0.75 µM), ADP (4.3 µM), platelet activating factor (800 nM) and collagen (638 nM) in a dose-dependent manner. Egyptian mimosa or Acacia nilotica or Vachellia nilotica is a leguminous and complex species tree of great socio-economic and ecological significance in the world. of selected sudanese medicinal plants with emphasis on, Del. reported to be very rich in saponins and tannins (18). Blood urea nitrogen (BUN) level was 4.86 and 6.59% lower in T1 and T2 group as compared to control and inversely proportional with level of supplement in ration. A micropropagation system was developed for Acacia nilotica by comparing MS and B5 media effects on growth. herbs nephropathy”? The effects on mortality were monitored after 48 h. The plant extract and all of the pure tested compounds were active against O. ochengi (LC50 ranging from 1.2 to 11.5 μg/mL on males) and C. elegans (LC50 ranging from 33.8 to 350 μg/mL on wild type). Res. Leaves extracts exhibited considerable bacteriostatic activity against two Gram-positive and three Gram-negative strains. Phytochemical properties and, hypoglycemic acticity of the aqueous and fractionated, blood glucose level in normoglycemic Wistar albino ra. Nephrotoxicity and Chinese Herbal Medicine, Toxicity of Acacia Nilotica (Garad) to Nubian Goats, Phytochemical screening of selected medicinal plants used against diarrhea in Niger, West Africa, Anti-Onchocerca and Anti-Caenorhabditis Activity of a Hydro-Alcoholic Extract from the Fruits of Acacia nilotica and Some Proanthocyanidin Derivatives, Entomological Monitoring of Rift Valley Fever Virus in Niger, Systematic evaluation of Ethnomedicinal plants from NIGER republic, Epidemiology of cholera and other Gastrointestinal diseases in Niger Republic. Worms were incubated in the presence of different concentrations of fruit extract, fractions and pure compounds. 2016;41(1-3):123-9. doi: 10.1159/000441268. The honeybee Acacia nilotica var. J Appl Pharm Sci. Research Article [Malviya et al., 2(6): June, 2011] ISSN: 0976-7126 Int. The pods of Acacia nilotica were successfully utilized for the extraction of tannins using a methanol/water extraction medium. The results showed that the stem bark extract of the plant possessed the active principles e.g. These results are in good accordance with the use of A. nilotica against nematode infections by traditional healers, herdsmen and pastoralists in Cameroon. Department of Biochemistry, Faculty of Medicine, University of Khartoum, PO Box 102, SudanSearch … The pods of Acacia nilotica were successfully utilized for the extraction of tannins using a methanol/water extraction medium. certain side effects (9,10). It belongs to a family: Fabaceae; genus: Acacia and spices: nilotica. Acacia nilotica is multipurpose nitrogen fixing tree legume that is widespread in Africa and Asia, and occurs in Australia. I mechanistic assays on ROS, gluta, carrier for intracellular delivery of biomolecular drugs. hemispherica is an endangered and endemic taxon reported from Southern Pakistan. We hope to valorize the tradi, Nowadays, cardiovascular diseases are highly prevalent in human communities. Department of Biochemistry, Faculty of Medicine, University of Khartoum, P.O.Box 102, Sudan . 2000;95(12):3634-7. doi: 10.1111/j.1572-, cells. In this study, hypertension, Iran, ethno-botany, medicinal plants, and traditional medicine were used as key words to search in Web of Science, PubMed, Scopus, EBSCO and EMBASE to select relevant articles. Medicinal and nutritional The subfamily of the Acacia nilotica is Mimosoideae [18]. The purpose of screening is to justify, authenticate and validate the use of Indian Medicinal Plants in ethno-medicinal or folklore as traditional treasure to cure various ailments. The Acacia species selected were Acacia nilotica, Acacia seyal and Acacia senegal. Nearly a third of the American population admit to using some form of complementary or alternative medicine, with many using them in addition to prescription medications. Effect of tannin-, Malan E. Derivatives of (+)-catechin-5-gallate from the, Manzo LM, Moussa I, Ikhiri K. Phytochemical screening, Deshpande SN, Kadam DG. Phytochemical analysis, (Benth.) It is called as Bagaruwa in Hausa and is a great source of livelihood. 2013;5(4):123-30. doi: Al-Mustafa ZH, Dafallah AA. Results: In this study, a total of 16 different types of medicinal plants were studied in 35 clinical trials which had inclusion criteria were evaluated. ASSIGNMENT ON REVIEW OF RESEARCH PAPER Isozyme variation in progenies of plus trees of Acacia nilotica ssp. Almost all its parts are used in medication … The hypoglycemic effects of this plant have been attributed to its role in stimulating the islets of Langerhans to produce more insulin. While Rasool et al reported the hemolytic effect of, lysis of the erythrocytes by plant extracts was found to be, peripheral blood mononuclear cells (PBMC) to evalua, cell lines as model to evaluate the cytotoxicity effect of fruit, van den Bout-van den Beukel et al evaluated the effects, electron transport chain activity with the aid of Alama, Blue, Hoechst 33342, calcein-AM uptake, gl, On the basis of the results obtained from these five assa, the plant was found to be highly toxic (10). The experimental animals were fed graded level of A. nilotica pod meal (0%, 10%, 20% and 30%) mixed in concentrate mixture equivalent to tannin concentration of 0%, 1.91%, 3.82% and 5.73% in the total mixed ration I, II, III and IV, respectively, but ad libitum measured quantity of green sorghum fodder (Sorghum bicolor) feeding. Natural product manufacturers are not responsible for proving safety and efficacy, as the FDA does not regulate them. The metabolic status of the animal was not affected with the supplementation of babul pod meal, however, lower serum creatinine level and remarkable reduction in nematode, as well as protozoan egg count in the treatment group, showed good health impact of babul pod. Luffa cylindrica is the botanical name of the sponge gourds and belongs to Cucurbitaceae family. Journal of Hazardous, Toxic, and Radioactive Waste, 21. Join ResearchGate to find the people and research you need to help your work. Powdered air-dried heartwood of A. nilotica var. Evid Based Complement Alternat, Linn. The present paper describes a systematic review protocol for the assessment of the hypoglycemic effects of A. nilotica. Abstract Acacia nilotica was assessed for active principles. The high costs and toxicity of synthetic drugs have stimulated renewed interest in plant substitutes. J. A mini-review on the most important effective medicinal plants to treat hypertension in ethnobotanic... Effect of medicinal plants in the treatment of primary dysmenorrhea in Iran: A review article. Medicinal and nutritional properties are the characteristics of Luffa cylindrical and … Its pharmacological properties are reported in many studies, but the fact remains that the plant can be just as toxic as any modern pharmaceutical drug. It is imperative that natural product use be monitored closely in all patients. Abstract Acacia nilotica Lam (Mimosaceae) indigenously known as 'Babul' or 'Kikar' is a proverbial, medium sized tree and is broadly scattered in tropical and subtropical countries. Conclusion The antimicrobial action was compared with the effect of doxycycline antibiotic. In this study, the hydro-alcoholic fruit extract (crude extract (CE)) and, one of the main constituents in its most active fractions, (+)-catechin-3-O-gallate (CG), as well as four related proanthocyanidins, (-)-epicatechin-3-O-gallate (ECG), (+)-gallocatechin (GC), (-)-epigallocatechin (EGC) and (-)-epigallocatechin-3-O-gallate (EGCG), were assessed for their potential in vitro anthelmintic properties against the free-living model organism Caenorhabditis elegans and against the cattle filarial parasite Onchocerca ochengi. In. 2(5), 20-24, May (2014) Int. Follow Published on Dec 8, 2015. J Altern Com. All rights reserved. Influence of aq, crude extracts of medicinal plants on the osmotic stability. Hypertension is a multifactorial disease which causes a mortality twice higher than general population. Acacia Nilotica is a good herbal treatment for curbing and preventing Brain related ailments like Meningitis. Results: Twenty-three plant species have been reported to possess active molecules against multi-drug resistant (MDR) isolates of Mtb. Ahmed El‐Tahir. 2010;4(12):1169-75. doi: G, et al. Evaluation of Root Extract of Acacia nilotica on Haematological and Lipid Profile in Rats, Effect of feeding Acacia nilotica pod meal on hematobiochemical profile and fecal egg count in goats, Efficacy of Acacia nilotica Extracts Towards Microbicidal Activity against Pathogens, Acute Toxicity and Effects of Aqueous Pod Extract of Acacia nilotica on Some Haematological Parameters and body weight in Rats. Its pharmacological properties are reported in manystudies, but the fact remains that the plant can be just as toxic as any modern pharmaceuticaldrug. This review is aimed … In addition, anthraquinones, flavonoids, and glycosides from herbs also are known to cause kidney toxicity. … A study cond, will enhance the therapy of several diseases such as cancer, diabetes and other inflammatory diseases (26). The findings of this study indicated that in Iran 40 plants in various provinces are used to treat hypertension. The creatinine level was 20.17% lower in T2 group as compared to control. Results: Few studies have reported the toxicity potential of A. nilotica and most with very limited information. Jum, 100, 200, and 300 mg/kg body weight were orally an, mice daily for 28 days. • Hepatitis C virus (HCV) belonging to the family Flaviviridae has infected 3% of the population worldwide and 6% of the population in Pakistan. However, there is no scientific data supporting this ethnomedical use of Acacia nilotica. Manisha … The decrease in BUN reflected good dietary protein metabolism happened in animals supplemented with babul pod meal. The alkaloids were present in all plants except Sclerocarya birrea. is a review study. Invasive Acacia nilotica A Problematic Weed is a Source of Potent Methyl Gallate. The fruits of this plant have flat seeds and black in colour which is enclosed by group of fibers [19]. This research was conducted to extract, isolate and identify major compounds from heartwood of Acacia nilotica var. This article aims to explain the uses and bioactivity of A. compactum. The outcomes will be … A study on the toxicology, Lompo-Ouedraogo Z. 1999;354(9177):481-2. doi: 10.1016/s0140-6736(99)03380-, with bee pollen contained in nutritional supp, Ther Apher Dial. Hypoglycemic effects of Acacia nilotica in type II diabetes: a research proposal. tannin (TGAN) for removal of Cu. Abstract. The minimum inhibitory concentration ranged between 0.5 and 1 mg, while … : 2010117052 Degree: M.Sc. Abstract-The biosorption of Cu (II) from aqueous solutions by Acacia nilotica tannin gel (TGAN) was investigated as a function of initial pH, contact time, initial metal ion concentration and tannin extract concentration. We have focused on products that have been associated with direct renal injury, immune-mediated nephrotoxicity, nephrolithiasis, rhabdomyolysis with acute renal injury, hepatorenal syndrome, and common adulterants or contaminants that are associated with renal dysfunction. Copyright © 2020 Author(s) retain the Data were analyzed qualitatively. It was observed that all eight plants contained flavonoids, tannins, steroids, terpenoids, saponins and phenols. Sci Pharm. Healthcare practitioners must play an active role in identifying patients using natural products and provide appropriate patient education. 2017;10(4):81-92. doi: 10.12692/ijb/10.4.81-92. Animal exposure to toxic substances can im, particular organ or organs function in man, modern pharmaceutical medicines, medicinal plants were, also reported to have the potential to cause or, the use of inherently toxic medicinal plan, certain key organs, to process and elimin, these substances. Antidiabetic activity and safety of aloe. View Acacia Nilotica Research Papers on Academia.edu for free. Review of research paper 1. Some of the nephrotoxic components from herbs are aristolochic acids and other plant alkaloids. In female rats, the dose of 250 mg/kg b.wt of the extract produced significant increase in Hb and PCV. A b, (e.g. Given the fact that medicinal plants have long been used to treat hypertension and are currently being administered for this disease, we sought to report the mostly effective and important medicinal plants on, Introduction: Primary dysmenorrhea is a common problem in women of reproductive age that effect their quality of life and social activities. It is an important riverine tree in India, Sudan and Senegal, where it is planted for timber. Africa. 2015;7(7):380-. Willd, Acacia scorpioides W.Wight, Mimosa arabica Lam., Mimosa nilotica L., and Mimosa scorpioides L [6]. However, concerns exist surrounding the safety of natural products. the traditional medicine involves the use of different plants or the bioactive Results: The extract at 500mg/kg body weight, produced significant increase in red blood cells (RBC), white blood cells (WBC), hemoglobin (Hb) and packed cell volume (PCV) compared to the control in male rats. (2017) Adsorption of Indigo Carmine Dye onto Acacia Nilotica (Babool) Sawdust Activated Carbon. online media used Web, Scopus, Pubmed, and scientific journals. Brenan. The present review aims to provide up-to-date a summary of the phytochemical and pharmacological usage of Acacia nilotica tree.Acacia nilotica is an important multipurpose medicinal plant; it was used for the treatment of various diseases and is widely distributed throughout the tropical and sub-tropical regions. 2011;2011:274741. doi: 10.1093/ecam/neq060. A computational study targeting the mutated L321F of ERG11 gene in C. ... Phenolic compounds have been documented as a best source to target yeasts especially the compounds from Acacia nilotica, a medicinal shrub in tropical countries which is … Tree of them have reported serious deleterious toxic effects of certain parts of the plant on major organ systems such as kidney and liver. To value the traditional use of these plants, different organs were collected, dried, powdered and separately extracted using water, methanol and ethanol. Among, them are tannins, saponins, terpenoid, cyanogenic, t, amino acids, glycosides, alkaloids, coumarins, flavono, (6–8). In, pods. is bright yellow flowers in round heads and is prolific, and can occur a number of times in a season The blooming period is October to December and March to April. Box 2404, Khartoum, Sudan. Acacia nilotica Willd. Plants and lactation: from tradition. Presented by: : Zohaib HUSSAIN Hepatitis C virus (HCV) belonging to the family Flaviviridae has … J Pure Appl Sci. Bark samples from bulk collections of the three Acacia species were extracted with water, 80% methanol and 70% acetone. Conclusion: Given that an increasing number of articles with acceptable credit and positive results have evaluated the fennel, so this plant can be safely used in the relief of pain in primary dysmenorrhea. Research Paper presentation on " Antiviral activity of Acacia nilotica against Hepatitis C Virus in liver infected cells" 1,012 views. It is beneficial in combating pain in the Ear. Since today using of medicinal plants for treatment of primary dysmenorrhea has been addressed, so this study was performed with aim to determine the effect of medicinal plants in treatment of primary dysmenorrhea as a review article in Iran. Justification. Chinese herbal medicine has been practiced for the prevention, treatment, and cure of diseases for thousands of years. International Journal of Scientific and Research Publications, Volume 2, Issue 9, September 2012 1 ISSN 2250-3153 www.ijsrp.org Plants in Relation to Salinity and their Interaction with Soil Water Stress Dhupper.R Amity Institute of Environmental Science, Amity University (Noida) Abstract- The growth response of Acacia nilotica, Albizzia lebbeck and Prosopis cineraria seedlings in relation to salinity … The hypoglycemic effects of this plant have been attributed to its role in stimulating the islets of Langerhans to produce more insulin. Acacia nilotica research paper defending your doctoral dissertation. Objective: This article elaborates on studying the activity of medicinal plants against different forms of Mycobacterium tuberculosis (Mtb) using, Amomum compactum Soland ex Maton is native plant in Indonesia, which is used as medicine and spices. (Chinese herbs nephropathy). The present paper describes a systematic review protocol for the assessment of the hypoglycemic effects of A. nilotica.Randomized and non-randomized placebo-controlled clinical trials, performed during 1999-2016 will be included. J. of Pharm. The res, significant elevation in oxaloacetate transamin, feathery degeneration of hepatocytes and destruction of, potential of the ethanol fruit extract of, treated at doses of 75, 100, 112.5, 125, 187.5, 250 and 500, for three weeks induced significant elevation in ur, mammalian cells have been used for high-throughp, Certain chemical constituents of medicinal plan, animal erythrocytes (44,72,73). 2010;14(1):93-7. doi: 10.1111/j.1744-, by a Brazilian variety of propolis. Seven plants were found to be active against intracellular Mtb and six against dormant bacilli. Phytomedicine and Clinical Research. Previous studies have confirmed the anti diabetic properties of Acacia nilotica. tree is 5 to 20 m (in humid zone) in high with a spherical, bark, gray-pink, exuding a reddish gum of lo. The hypoglycemic effects of this plant have been attributed to its role in stimulating the islets of Langerhans to produce more insulin. a tree belonging to the family Mimosaceae were reviewed. seed. It is against this background that this study was designed to evaluate the antidiabetic potential of aqueous leaf extracts of Acacia nilotica in alloxan induced Changes in body and o, hematological and biochemical parameters a, extract at 1 g/kg body weight significantly reduced body, oral administration at the same dose decreased levels of, platelets. lotica know as babul is the most important tree of the dried parts of India. Oral administration of the extract at 1 g/kg b, ALP and total bilirubin. Anti-free radical activities of kaempferol isola, of selected medicinal plants used against diarrhea in Niger, Delile with novel Kinase inhibitory activity, International Open. 2016;17(4):1-7. doi: 10.9734/EJMP/2016/31262. Molecules. The blood samples were collected from experimental goats during the feeding experiment for the examination of different hematological indices and serum biochemical profile to know the overall health status of animals and standard method was followed to analyze the samples. A. nilotica is an agroforestry and urban forestry tree species, which provide fruits, timber, fodder, gums and other services such shade, beauty, soil improvement. Conclusion: Overall, this review provided comprehensive information on what is known about the toxicity of A. nilotica and showed the necessity to conduct more advanced long-term-based toxicological studies. 2013;3(3):109-11. doi: extract in experimental African trypanosomiasis. The present paper describes a systematic review protocol for the assessment of the hypoglycemic effects of A. nilotica. Medical Sci. calcium channels. Acacia nilotica has been used traditionally for management of diabetes mellitus complications. Basic Clin Pharmacol, medicinal des plantes Africaines, Afrique de l’, in sahelian zone of Cameroon, Central Africa. Fecal sample was collected directly from the anus of goats by inserting middle finger and kept the samples in labeled polythene bag. Am J Kidney Dis. Haemonchus and Coccidian egg count was significantly reduced (p<0.01) in T2 and T3 group followed with T1 as compared to control group. Int J Inn, bacteriological parameters in goats. Possible reasons for organ injury as a result of medicinal plant intake. The pod extract of A. nilotica was obtained by Soxhlet extract using distilled water as solvent. Stem bark as part of A. nilotica appeared to be the most cited to cause observable clinical signs of toxicity and organs lesions. Alternative methods for the median lethal dose, (LD(50)) test: the up-and-down procedure f, 1998;106 Suppl 2:497-503. doi: 10.1289/ehp, Am Soc Nephrol. human being. The feeding of babul pod meal did not address significant changes about the hematological parameters among various treatment groups. Tripti, B.G. Acacia nilotica. Egyptian mimosa or Acacia nilotica or Vachellia nilotica is a leguminous and complex species tree of great socio-economic and ecological significance in the world. Acacia nilotica. All rights reserved. The pods of Acacia nilotica are reported helpful in removing catarrhal matter and phlegm from bronchial tubes; African zulu take bark of Acacia nilotica for cough treatment 36. nilotica is a pantropical and subtropical genus with species abundant throughout Asia, Australia, Africa and America. 2009;2(1):135-8. doi: 10.4314/ba, and d,l-methylphenidate in beagle dogs. Masai people/tribe believes Acacia nilotica is a good aphrodisiac and the root is said to cure importance. Agric Biol Chem. The results showed that the stem bark extract of the plant possessed the active principles e.g. Phytochemical analysis of acacia nilotica plant confirm the presence of various Acacia nilotica ( Figure2)is popular as an agroforestry tree, either sown in lines 5 m apart in agricultural fields, or on field crop boundaries. 2017;4(3):e108-13. longifolia: DMT, NMT, tryptamine, other alkaloids : Acacia nilotica: One published report of DMT in the leaf may derive from a misreading of a paper that found no DMT in leaves of this species. Hair Fall. Med. European J Biol Sci. Additionally, the results of cytotoxicity tests with the Caco-2 cell line (CC50 ranging from 47.1 to 93.2 μg/mL) confirmed the absence of significant toxicity of the crude extract and pure compounds. 2+ from aqueous solution, and also find biosorption of binary and tertianary metal solution onto the surface of. (2017) Adsorption of Indigo Carmine Dye onto Acacia Nilotica (Babool) Sawdust Activated Carbon. B. subtilis was the most susceptible to the plant extract while Candida albicans was the most resistant. Hemolytic, rat and human erythrocytes. doi: 10.1055/s-. Some studies have also shown the dual activity (anti-HIV and anti-TB) of plants. 2019; 8(3): 163-172. were reviewed. About Acacia nilotica Plant : Habit : A medium-sized almost evergreen tree, straight or crooked, armed tree with dark-blackish-brown, irregularly, longitudinally fissured bark. Conclusion: We emphasize on identifying plants based on traditional uses and testing their extracts/phytomolecules against MDR strains, intracellular Mtb as well as against dormant Mtb. novel compounds. adstringens was extracted with methanol/water, 4:1 and the extracted was then purified using chromatographic techniques (column and paper … but which is edible, and is used in confectionery making. Several studies ha, reported the contribution of certain medicinal pla, hours) during the first 24 hours post trea, in rats treated acutely with 50-500 mg/kg o, toxicity in mice at doses of 50, 100, 200, 500, 1000 mg/. (Redirected from Acacia nilotica) Vachellia nilotica (commonly known as gum arabic tree, babul, thorn mimosa, Egyptian acacia or thorny acacia) is a flowering plant tree in the family Fabaceae. The kidney manifestations of nephrotoxicity associated with herbal medicine include acute kidney injury, CKD, nephrolithiasis, rhabdomyolysis, Fanconi syndrome, and urothelial carcinoma. The tree has fine gray spines in axillary pairs (usually 3, to 12), 5 to 7.5 cm long in young trees. It is very important to dispose sufficient knowledge on what are reported concerning itstoxicity profile. 2001;38(5):E26. The potential biological functions of A. nilotica have long been described in traditional system of medicine. © 2008-2020 ResearchGate GmbH. and biochemical parameters in plasma, liver an. ABSTRACT ASSIGNMENT ON REVIEW OF RESEARCH PAPER Isozyme variation in progenies of plus trees of Acacia nilotica ssp. This article is published under the terms of the Creative All figure content in this area was uploaded by Lawaly Maman Manzo, All content in this area was uploaded by Lawaly Maman Manzo on Jul 14, 2019. Gen Pharmacol. berghei in mice. Paper presentation on Antiviral activity of Acacia nilotica against Hepatitis C Virus in liver infected cells Presented by: : ZohaibHUSSAIN COMSATS 2. A. nilotica could be a potential source of antimicrobial agents. 2, Issue 6: June: 2011, 830-837 830 INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES Medicinal attributes of Acacia nilotica Linn. Six studies suggest that the beneficial effects of plant extracts are due to their wide array of immuno-modulatory effects manifested by the higher expression of cytokines. Diarrhea, weight loss, agitation, heart, spleen, brain, testicles, etc were also reported in. Protective Effect of Acacia nilotica (L.) against Acetaminophen-Induced Hepatocellular Damage in Wistar Rats Hypoglycemic effects of Acacia nilotica in type II diabetes: a research proposal BMC Research … Indica, when external circumstances or internal condi, clinical signs of disease are often quite similar fo, metabolites that can be toxic to body systems when, took without cautious (1,5). Brenan is the most common form in east tropical Africa. Of the studies that, deleterious toxic effects of certain parts of, in certain hematological and biochemical parameters in, anomalies were observed after long-term exposure and, Overall, because of the remarkable increasing deman, final version and confirmed for the publica, analysis have been carefully observed by author. The comparative in vitro antimicrobial activity of ethanol and chloroform leaves extracts from Acacia nilotica L. was studied. incites the curiosity of many researchers. This study was conducted to observe the effect of feeding Acacia nilotica pod meal on hematobiochemical profile and gastrointestinal parasitic load in growing goats. A biology of acacias. kraussiana (Benth.) J Med Plant Res. 100g of. Botanical Name : Acacia nilotica (L.) Delile Synonyms : Acacia Arabica Willd. Brenan is the most common form in east tropical Africa. The administration of the extract at 3000 mg/kg body weight in the acute toxicity study did not produce any death in the treated rats, indicative of the low toxicity of the extract. Background: Results The synonyms are Acacia arabica (Lam.) The bark is rich in tannins (12-20%), terpenoids, reported the extraction, purification and identification of, plant extract was reported (25). Details on the studies that reported both, signs alterations in the exposed living animals. Seven plants were synergistically effective when combined with anti-TB drugs. Vachellia nilotica (commonly known as gum arabic tree, babul, thorn mimosa, Egyptian acacia or thorny acacia) is a flowering plant tree in the family Fabaceae.It is native to Africa, the Middle East and the Indian subcontinent.It is also a Weed of National Significance in Australia (an invasive species of significant concern in Australia,) as well as a Federal Noxious Weed in the United States. The crown may be flattened or rounded. This review is aimed to provide comprehensive summary (all-in-one) of what have been reported about the toxicity of A. nilotica and to determine the necessity or not to conduct more toxicological studies in a further step toward rationalizing its medicinal use. Hence an urgent conservation strategy is required due to exposure of the taxon to habitat loss and its over-exploitation. Introduction: Acacia nilotica is a valuable plant with medicinal properties that increasingly is bright yellow flowers in round heads and is prolific, and can occur a number of times in a season The blooming period is October to December and March to April. Most of the medicinal herbs reviewed in the studies had flavonoid compounds with analgesic and anti-inflammatory effect that had desirable effect on dysmenorrhea pain relief. Plant extracts from Gardenia lutea, Haplophyllum tuberculatum, Cassia tora, Acacia nilotica and Aristolochia bracteolata possessed IC 50 values less than 5 µg/mL on both tested strains. treatment of fungal infections. in locomotion, a decrease in sensitivity to touch, reported the same major observable clinical signs in rats, clinical signs reported due to the treatment (42). The antimicrobial activity of the extracts was assayed against Streptococcus viridans,Staphylococcus aureus, Escherichia coli, Bacillus subtilis and Shigella sonnei using the agar diffusion method. It gives accurate information regarding severity of infection. Am J K. 2005;46(6):e125-9. The present study attempted to investigate the protective effect of A. nilotica against acetaminophen-induced hepatic damage in Wistar rats. Several factors contribute to the nephrotoxicity of herbal medicines, including the intrinsic toxicity of herbs, incorrect processing or storage, adulteration, contamination by heavy metals, incorrect dosing, and interactions between herbal medicines and medications. Our study indicates that the all medicinal plants selected in the present work are rich in phytochemicals like alkaloids, flavonoids, tannins, steroids, terpenoids, saponins and phenols. 2013;13(2):111-7. doi: 10.3923/jms.2013.111.117. Few number of studies, conducted elsewhere have reported erythrocyte toxicity, highest hemolytic activity (8.9 ±0.16). Possessed the highest activity ( anti-HIV and anti-TB ) of plants, seyal... Nilotica root has been used traditionally for management of diabetes mellitus complications induced diarrhea in.. The extract at varying doses for 21 days subtilis was the most form... For Acacia nilotica ( L. ) Delile Synonyms: Acacia Arabica Willd but the remains! Babool ) Sawdust Activated Carbon uses in Sudan Zohaib HUSSAIN, research Student Biotechnology. The comparative in vitro antimicrobial activity of a hydro-alcoholic extract from, guided fractionation and anti-inflammatory of., 8 % Acacia diet for 2 and 4 weeks in combating pain in the groups treated various! Is edible, and d, l-methylphenidate in beagle dogs, analysis of aqueous and fractionated, glucose... Have long been described in traditional rural and agro-pastoral systems ( Shittu 2010. Multifactorial disease which causes a mortality twice higher than general population potential vector of in! In addition, anthraquinones, flavonoids, and patients require appropriate postexposure screening on Academia.edu free... The pod extract was relatively safe and its over-exploitation bark extract of, is due to herbal! 250 mg/kg b.wt in both male and female rats in C provides the health application of Acacia nilotica is nitrogen!, Sayed an, Ahmed MM are used in medication … Acacia nilotica is a valuable plant with properties. An aqueous extract from the fruits of this study provides the health application of Acacia nilotica ( L. Delile., cardiovascular diseases are highly prevalent in human communities on natural products that been..., agitation, heart, spleen, brain, testicles, etc were also carried out not significant. Nilotica aqueous pod extract was relatively safe and its over-exploitation fruit extract, and... Bioaktivitas amomum compactum is an endangered and endemic taxon reported from Southern Pakistan and identify major compounds from heartwood Acacia... And most with very limited information 4 ( 1 ):9-13. doi: 10.1159/000441268 costs... For thousands of years plants with emphasis on, Del been associated with fluconazole resistance with bioactive compounds from nilotica. Providers of their natural product manufacturers are not responsible for medicinal purpose is justified sites... And occurs in Australia significant ( p < 0.01 ) in T2 group as compared to control standard.. Registration no to help your work in identifying patients using natural products that have been attributed its! Plant with medicinal properties that increasingly incites the curiosity of num, scientists to further investigate its pot with drugs... Key words: Acaacia nilotica, it is an important riverine tree in India tannins alkaloids! Increase risk for future uroepithelial cancers, and occurs in Australia seven were... 2005 ; 46 ( 6 ): 163-172. were reviewed to nephrotoxic herbal medicine use in patients with unexplained or... By a Brazilian variety of propolis Hausa and is a leguminous and species... And six against dormant bacilli valorize the tradi, Nowadays, cardiovascular diseases highly! Des plantes Africaines, Afrique de l ’, in sahelian zone of Cameroon as anti-filarial remedies traditional... In medication … Acacia nilotica, it is beneficial in combating pain in the groups with!, CCFN, INRAN, LASDEL, and scientific journals total bilirubin of the taxon to habitat and... And 1 mg, while … Acacia nilotica by comparing MS and B5 effects... Group as compared to control for Acacia nilotica effects of A. nilotica among health p, substances 5... This article, tannin, steroid, triterpenoid and phenol contents in all these plants found! 1998 ; 4 ( 12 ):1169-75. doi: 10.1080/10915810305100 l ’, in zone. Plant possessed the highest activity ( IC 50 = 1.5 µg/mL ) dose‐dependent ( 3–30 mg/kg ) fall arterial. Acacia scorpioides W.Wight, Mimosa Arabica Lam., Mimosa Arabica Lam., Mimosa Arabica Lam., Mimosa nilotica L. studied... Results the feeding of babul pod meal did not address significant changes about hematological... Due to high tannin levels, 8 % Acacia diet for 2 and 4.. A. compactum there is no scientific data supporting this ethnomedical use of natural products that have been associated fluconazole! A dose‐dependent ( 3–30 mg/kg ) fall in arterial blood pressure in saponins and phenols journal., saponins and glycosides from herbs also are known to cause observable clinical signs toxicity! This situation, has given rise to inquietude among health p, substances ( 5 like... In experimental African trypanosomiasis the articles which obtained the score of > with. Candida albicans was the most common form in east tropical Africa nilotica pods ( an ) caused a (. Few number of studies, conducted elsewhere have reported serious deleterious Toxic effects certain. All eight plants contained flavonoids, tannins, alkaloids, saponins and tannins ( 18 ) 5. Of yesterday, new TR endangered and endemic taxon reported from Southern Pakistan the! Malviya et al., 2 ( 6 ): June: 2011, 830-837 830 acacia nilotica research paper... Emphasis on, Del Africa and Asia, and is a valuable plant with medicinal properties that incites. Nilotica have long been described in traditional rural and agro-pastoral systems (,! On acetaminophen-induced hepatotoxicity is still unknown kidney and liver India, Sudan closely in patients. ; like ; Download... Zohaib HUSSAIN, research Student of Biotechnology COMSATS... And complex species tree of the Leguminosae family tree with many traditional uses in.... Tree of them have reported the toxicity potential of A. nilotica against nematode infections by traditional,. Hematological parameters among various treatment groups brain related ailments like Meningitis plant species have associated! A family: Fabaceae ; genus: Acacia nilotica and leaves of Tapinanthus dodoneifolius, growing in Nigeria by MS! Of calcium influx through membra also a popular ornamental avenue tree in India and glycosides 2014 ).! Protective effect of A. nilotica reported elsewhere were reviewed are aristolochic acids and other inflammatory diseases ( 26 ) that! Issue 6: June, 2011 ] ISSN: 0976-7126 Int the active principles e.g EISAA and. Information about the hematological parameters among various treatment groups in saponins and glycosides containing aristolochic acid may increase risk future! Also shown the dual activity ( 8.9 ±0.16 ) novel chemical compounds for reseach. 0.05 ) in the rainy season Isozyme variation in progenies of plus trees of Acacia nilotica var a source... Of the sponge gourds and belongs to a family: Fabaceae ; genus: Acacia and spices relates its. Pod extract of Acacia nilotica in alloxan: 10.1080/10915810305100 may ( 2014 ) Int with emphasis on Del! Extract of the taxon to habitat loss and its over-exploitation costs and toxicity of synthetic have. Report and review of herbal hepatotoxicity, Gastroenterol nilotica and leaves of Tapinanthus dodoneifolius, growing Nigeria... These plants were estimated using standard methods justify their traditional usage against diarrhea Meningitis... The use of A. nilotica have long been described in traditional rural and systems. Delile Synonyms: Acacia nilotica against acetaminophen-induced hepatic damage in Wistar rats crude extracts of Acacia nilotica against Hepatitis Virus! Mcmaster Technique for eggs per gram against two Gram-positive and three Gram-negative strains extract varying! And identify major compounds from heartwood of Acacia nilotica ( L. ) Delile Synonyms: Acacia Arabica Willd attributes Acacia! Aqueous leav, extracts showed hemolytic effect with an IC, ( 26 ) innocuous... 2 and 4 weeks be a potential source of Potent Methyl Gallate prevalent in human.! Crude extracts of medicinal plant intake and identify major compounds from heartwood of Acacia nilotica pods ( )! Diseases ( 26 ) leaves extracts exhibited considerable bacteriostatic activity against two Gram-positive and Gram-negative. Remains that the stem bark extract of the aqueous and fractionated, blood glucose in.: nilotica active ingredients with varying degrees of side effects d, l-methylphenidate beagle... Belonging to the aqueous methanolic extract ):81-92. doi: in a Chinese patient: to! All its parts are used in medication … Acacia nilotica fruits with high tannin levels, 8 % diet... Activated Carbon dollar industry 2320 –7353 Vol changes about the hematological parameters among various treatment groups that this study that... Signs of toxicity and organs lesions occurs naturally and is used in the Ear, but the fact that. For the assessment of the extract at 1 g/kg b, ALP and bilirubin... L [ 6 ] selected Sudanese medicinal plants with emphasis on­Acacia nilotica in:... Inserting Middle finger and kept the samples in labeled polythene bag department of Biochemistry, of! 300 mg/kg body weight were orally an, Ahmed MM ) Sawdust Activated.. Copyright © 2020 Author ( s ) retain the copyright of this study was designed to the! Nilotica var the highest activity ( 8.9 ±0.16 ) Sclerocarya birrea article [ Malviya et al., (. Great source of livelihood should consider herbal medicine is not acacia nilotica research paper socio-economic and ecological significance in the.... That this study was designed to evaluate the antidiabetic potential of A. compactum can be through in-situ and ex-situ conserve! Bioactive compounds from heartwood of Acacia nilotica is Mimosoideae [ 18 ] with bioactive compounds from heartwood of Acacia or... Acid may increase risk for future uroepithelial cancers, and glycosides from herbs also are known to cause toxicity! 80 % methanol and 70 % acetone ), 20-24, may ( 2014 ) Int have. Of yesterday, new TR remedies by traditional healers, herdsmen and pastoralists in Cameroon important tree of the family! ):135-8. doi: 10.1089/acm.1998.4.1-9 long been described in traditional system of,... These results are in good accordance with the extract produced significant increase in body weight gain in the.... Contents in all patients the assessment of the three Acacia species selected were Acacia nilotica var stimulated! Activity ( anti-HIV and anti-TB ) of plants as medicine and spices:.!

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